HCID 19809645, compound → HCID 19809647, compound

HRID 374300Notes

Reaction equation

HRID 374300 reaction equation
[CH2:1]([O:5][C:6]1[CH:11]=[C:10]([CH3:12])[C:9]([O:13]CC2C=CC=CC=2)=[CH:8][C:7]=1[CH3:21])[CH2:2][CH2:3][CH3:4].[H][H]>CO.[Pd]>[CH2:1]([O:5][C:6]1[C:7]([CH3:21])=[CH:8][C:9]([OH:13])=[C:10]([CH3:12])[CH:11]=1)[CH2:2][CH2:3][CH3:4]

Participants

5

Reactant 2

HCID 19809645HCID 19809645, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 19809647HCID 19809647, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A solution of 11.2 g (39.5 mmol) of 1 butoxy-2,5-dimethyl-4-(phenylmethoxy)benzene (Example L) in 100 mL of methanol containing 1 g of 20% palladium on carbon is shaken under three atmospheres of hydrogen for 1 hour. The catalyst is removed and the solvent evaporated in vacuo to afford 7.6 g of the title compound; mp 43°-45° C.

Workup

  1. customThe catalyst is removed
  2. customthe solvent evaporated in vacuo

Sources & evidence

ORD record
ord-bfb306d4100147fabc2339e8015e88f7
Source dataset
uspto-grants-1992_11
Patent number
US05166398

Reaction notes

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