Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 374319Generated: October 30, 2026

N-[4-pivaloyloxymethoxycarbonyl-(R*,R*)-2,4-dibenzylbutyryl]-L-leucine benzyl ester → HCID 14997138, compound

https://huagongshe.com/reaction/374319

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-[4-pivaloyloxymethoxycarbonyl-(R*,R*)-2,4-dibenzylbutyryl]-L-leucine benzyl esterHCID 14997137—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 14997138HCID 14997138—

Reaction Steps

0.85 g of N-[4-pivaloyloxymethoxycarbonyl-(R*,R*)-2,4-dibenzylbutyryl]-(L)-leucine benzyl ester in 20 ml of ethanol is hydrogenated at atmospheric pressure in the presence of 0.1 g of 5% palladium on carbon. The reaction is filtered and evaporated to give N-[4-pivaloyloxymethoxycarbonyl-(R*,R*)-2,4-dibenzylbutyryl]-(L)-leucine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05166212
Source datasetuspto-grants-1992_11
ORD IDord-1a7ef3477c6645669ba81a0e001e592c
Source noteuspto-grants-1992_11