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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 37439Generated: October 28, 2026

ethyl p-(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-7-carboxamido)benzoate → p-(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-7-carboxamido)benzoic acid

https://huagongshe.com/reaction/37439

Reaction equation

Participants

RoleNameHCIDCharge
Reactantethyl p-(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-7-carboxamido)benzoateHCID 19935413—
ReactantPotassium hydroxide ethanol waterHCID 23714421—
Productp-(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-7-carboxamido)benzoic acidHCID 18990063—

Reaction Steps

Hydrolysis of the foregoing ester with potassium hydroxide/ethanol/water in analogy to Example 57 gave p-(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-7-carboxamido)benzoic acid, melting point 274°-276° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05420273
Source datasetuspto-grants-1995_05
ORD IDord-ee93df0709024f47a9424441cd4335d9
Source noteuspto-grants-1995_05