Methanesulfonic Acid → HCID 178491136, compound

Participants

Reaction Steps

Methanesulfonic acid (7.8 ml; 0.120 mol) is introduced into a suspension of veratrylguanidine (25 g; 0.119 mol) in 240 ml of methanol. The mixture is stirred at room temperature for one hour. The methanol is evaporated under vacuum, the oil obtained is precipitated by stirring for 15 min in tetrahydrofuran. The white solid is filtered, rinsed with tetrahydrofuran and ether and then dried under vacuum. 30 g of veratrylguanidine methanesulfonate are obtained with a yield of 82%.

Provenance & Evidence