Hydrochloric Acid → HCID 18997197, compound

Participants

Reaction Steps

A solution of 1.30 g of methyl 4-[3-(4-chlorophenyl)-2-oxooxazolidin-4-yl]methoxybenzoate (compound 176) obtained in Example 22 in 18 ml of acetic acid and 10 ml of concentrated hydrochloric acid was refluxed with heating for 24 hours. The reaction mixture was concentrated under reduced pressure and the obtained residue was recrystallized from acetic acid-water to give 0.80 g of the title compound (compound 179) in a yield of 64%.

Provenance & Evidence