Acetone → HCID 18996994, compound

HRID 374639Notes

Reaction equation

HRID 374639 reaction equation
[OH:1][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][C:12]=3O)[C:7](=[O:18])[C:6]=2[CH:5]=[C:4](CO)[CH:3]=1.[C:21](=[O:24])([O-])[O-].[K+].[K+].[O-]S([O-])(=O)=O.[Ca+2].S(OC)([O:36][CH3:37])(=O)=O.[CH3:40]C(C)=O>>[CH3:40][O:1][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][C:12]=3[O:36][CH3:37])[C:7](=[O:18])[C:6]=2[CH:5]=[C:4]([CH2:21][OH:24])[CH:3]=1

Participants

6

Reactant 5

HCID 180AcetoneHCID 6497Dimethyl SulfateHCID 10207Aloe-emodinHCID 11430Potassium CarbonateHCID 24497Calcium Sulfate

Product 1

HCID 18996994HCID 18996994, compound

Procedure

9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-hydroxymethyl-anthracene (aloe-emodin) (45 g) and anhydrous potassium carbonate (225 g) were mechanically stirred in `Drierire` dried acetone (2.5 l) and `Drierite` dried dioxan (1l) before adding dimethyl sulphate (67.5 ml; 89.8 g). The mixture was heated at reflux for 20.5 hours.

Workup

  1. temperatureThe mixture was heated
  2. temperatureat reflux for 20.5 hours

Sources & evidence

ORD record
ord-83898be02da043478dd7f816321cd9ea
Source dataset
uspto-grants-1996_01
Patent number
US05480873

Reaction notes

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