2-Ethoxybenzoyl chloride → 2-(2-Ethoxybenzamido)-3-methylbenzamide

HRID 374781Notes

Reaction equation

HRID 374781 reaction equation
[NH2:1][C:2]1[C:10]([CH3:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5].[CH2:12]([O:14][C:15]1[CH:23]=[CH:22][CH:21]=[CH:20][C:16]=1[C:17](Cl)=[O:18])[CH3:13]>>[CH2:12]([O:14][C:15]1[CH:23]=[CH:22][CH:21]=[CH:20][C:16]=1[C:17]([NH:1][C:2]1[C:10]([CH3:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5])=[O:18])[CH3:13]

Participants

3

Reactant 2

HCID 30163972-Ethoxybenzoyl chlorideHCID 142218072-Amino-3-methylbenzamide

Product 1

HCID 185365992-(2-Ethoxybenzamido)-3-methylbenzamide

Procedure

The title compound was prepared from 2-amino-3-methylbenzamide (Chem. Pharm. Bull., 1988, 36, 2955) and 2-ethoxybenzoyl chloride following the procedure of Preparation 5 and was obtained as colorless crystals (71%), m.p. 197°-200° C. Found: C,68.80; H,5.99; N,9.36. C17H18N2O3 requires C,68.44; H,6.08; N,9.39%.

Workup

  1. customthe procedure of Preparation 5

Sources & evidence

ORD record
ord-b2fd3165b0224357bf996d9e9cdaaf9b
Source dataset
uspto-grants-1996_01
Patent number
US05482941

Reaction notes

Loading…