HRID374863

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8471

Triethylamine

C6H15N

$结构：CCCCCCCC/C=C\CCCCCCCC(=O)Cl$

HCID5364783

(9Z)-9-Octadecenoyl chloride

C18H33ClO

HCID15076672

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCC=CCCCCCCCC(=O)OCC(CCCCCCCCCC)NC(C)=O

HCID54534222

未命名化合物

收率 82.8%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

To a solution of 2.43 g of 2-ethanoylaminododecanol, 3 g of triethylamine in 50 ml of dichloromethane is added 3.2 g of oleoyl chloride. The reaction mixture is worked up as under Example 9 to give 4.2 g of product.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-930c7ce9323a4dae801e376d8c26b843
来源数据集: uspto-grants-1996_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05482965
来源说明: uspto-grants-1996_01

反应 SMILES

[C:1]([NH:4][CH:5]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[CH2:6][OH:7])(=[O:3])[CH3:2].C(N(CC)CC)C.[C:25](Cl)(=[O:43])[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]/[CH:33]=[CH:34]\[CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42]>ClCCl>[C:25]([O:7][CH2:6][CH:5]([NH:4][C:1](=[O:3])[CH3:2])[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])(=[O:43])[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH:33]=[CH:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42]