Hydroxyamine hydrochloride → HCID 86748008, compound

HRID 374932Notes

Reaction equation

[CH2:1]([CH:3]1[O:7][C:6]([C:9]2[CH:10]=[C:11]([S:15][C:16]3[CH:21]=[CH:20][C:19]([C:22](=O)[CH3:23])=[CH:18][CH:17]=3)[CH:12]=[CH:13][CH:14]=2)([CH3:8])[CH2:5][O:4]1)[CH3:2].Cl.[NH2:26][OH:27]>>[CH2:1]([CH:3]1[O:7][C:6]([C:9]2[CH:10]=[C:11]([S:15][C:16]3[CH:21]=[CH:20][C:19]([C:22](=[N:26][OH:27])[CH3:23])=[CH:18][CH:17]=3)[CH:12]=[CH:13][CH:14]=2)([CH3:8])[CH2:5][O:4]1)[CH3:2]

Participants

Reactant 2

HCID 443297Hydroxyamine hydrochloride

HCID 18996086HCID 18996086, compound

Product 1

HCID 86748008HCID 86748008, compoundYield 31%

Procedure

Using an analogous procedure to that described in Example 68, 4'-[3-(2-ethyl-4-methyl-1,3-dioxolan-4-yl)phenylthio]acetophenone was reacted with hydroxylamine hydrochloride to give 4'-[3-(2-ethyl-4-methyl-1,3-dioxolan-4-yl)phenylthio]acetophenone oxime in 31% yield as a gum.

Sources & evidence

ORD record: ord-b1d237af6d96477eaf0fec305d4acdf4
Source dataset: uspto-grants-1996_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05482966

Reaction notes

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