反应详情

In 2 ml of ethanol was dissolved 0.172 g of 3-amino-4,5-diethoxycarbonyl-2-phenyl-6-(tetrazol-1-yl)pyridine, whereto 1 ml of hydrazine monohydrate was added. The mixture was reacted at 90° C. for 2 hours. After 15 ml of ethanol was added, the mixture was cooled. The precipitate was collected by filtration and washed with ethanol. The thus-obtained precipitate was dissolved in 20 ml of hot water, and 0.7 ml of acetic acid was added. The mixture was cooled, and the resulting precipitate was collected by filtration, washed and dried, to give 0.11 g of the title compound as yellow crystals.

1. additionwas added
2. customThe mixture was reacted at 90° C. for 2 hours
3. temperaturethe mixture was cooled
4. filtrationThe precipitate was collected by filtration
5. washwashed with ethanol
6. dissolutionThe thus-obtained precipitate was dissolved in 20 ml of hot water
7. addition0.7 ml of acetic acid was added
8. temperatureThe mixture was cooled
9. filtrationthe resulting precipitate was collected by filtration
10. washwashed
11. customdried