HCID 15300849, compound → HCID 15300850, compound

HRID 375077Notes

Reaction equation

HRID 375077 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[S:11][N:10]=[C:9]([CH2:12][C:13]([O:15][CH3:16])=[O:14])[C:8]=2[CH:17]=1)([O-])=O>C(O)(=O)C.[Fe]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]2[S:11][N:10]=[C:9]([CH2:12][C:13]([O:15][CH3:16])=[O:14])[C:8]=2[CH:17]=1

Participants

4

Reactant 1

HCID 15300849HCID 15300849, compound

Product 1

HCID 15300850HCID 15300850, compound

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 176Acetic AcidSolvent

Conditions

Temperature
50 °C

Procedure

Iron (0.74 g, 13.3 mmol) is added portionwise to a solution of methyl 5-nitro-1,2-benzisothiazole-3-acetate (0.67 g, 2.7 mmol) in acetic acid at 50° C. The reaction mixture is stirred at 50° C. for several minutes, cooled and filtered through diatomaceous earth. The resultant filtrate, which contains the title product, is used in Example 22 without further purification.

Workup

  1. temperaturecooled
  2. filtrationfiltered through diatomaceous earth
  3. customis used in Example 22 without further purification

Sources & evidence

ORD record
ord-7cf72ff778754311a1c3b7b5c16d3d8e
Source dataset
uspto-grants-1996_01
Patent number
US05484763

Reaction notes

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