2-Propenoic acid, 3-(3-nitrophenyl)- → 151539-32-1

HRID 375324Notes

Reaction equation

HRID 375324 reaction equation
[NH2:1][C:2]1[C:3](=[O:16])[N:4]([CH2:13][CH2:14][CH3:15])[C:5](=[O:12])[N:6]([CH2:9][CH2:10][CH3:11])[C:7]=1[NH2:8].[N+:17]([C:20]1[CH:21]=[C:22]([CH:28]=[CH:29][CH:30]=1)[CH:23]=[CH:24][C:25](O)=O)([O-:19])=[O:18]>>[N+:17]([C:20]1[CH:21]=[C:22]([CH:28]=[CH:29][CH:30]=1)/[CH:23]=[CH:24]/[C:25]1[NH:1][C:2]2[C:3](=[O:16])[N:4]([CH2:13][CH2:14][CH3:15])[C:5](=[O:12])[N:6]([CH2:9][CH2:10][CH3:11])[C:7]=2[N:8]=1)([O-:19])=[O:18]

Participants

3

Reactant 2

HCID 683902-Propenoic acid, 3-(3-nitrophenyl)-HCID 50986055,6-Diamino-1,3-dipropyl-2,4(1H,3H)-pyrimidinedione

Product 1

HCID 5368233151539-32-1Yield 57%

Procedure

Substantially the same procedure as in Reference Example 1 was repeated using 4.0 g (17.7 mmol) of 5,6-diamino-1,3-dipropyluracil and 3.8 g (19.5 mmol) of 3-nitrocinnamic acid. Then, the resultant crude crystals were recrystallized from toluene to give 3.86 g (yield 57%) of Compound 34 as pale yellow needles.

Workup

  1. customThen, the resultant crude crystals were recrystallized from toluene

Sources & evidence

ORD record
ord-6d9e2a21d0b341a7b707913264eedcc6
Source dataset
uspto-grants-1996_01
Patent number
US05484920

Reaction notes

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