3-[4-(Trifluoromethyl)phenyl]prop-2-enoic acid → 155271-66-2

Participants

Reaction Steps

Substantially the same procedure as in Example 7 was repeated using 2.20 g (11.2 mmol) of 5,6-diamino-1,3-diethyluracil and 2.66 g (12.3 mmol) of 4-trifluoromethylcinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane/water to give 2.09 g (yield 49%) of Compound 136 as a white powder.

Provenance & Evidence