反应详情

A 500 ml autoclave was charged in a glove box (O2 content <1 ppm) with 27.0 g (175.0 mmol) of geraniol, 136 ml of methanol and 3.38 mg of Ru(CF3COO)2 [(R)-Tol-MeOBIPHEP] as the catalyst. The hydrogenation was effected at 20° C. and 60 bar. The conversion after 5 hours amounted to 100.0%. The hydrogenation solution was evaporated at 45° C./17 mbar and the crude product was distilled at 60°-65° C./0.03 mbar. There were obtained 26.7 g of (S)-citronellol as a colourless oil; e.e. 99.3%.

1. customwas effected at 20° C.
2. customThe hydrogenation solution was evaporated at 45° C./17 mbar
3. distillationthe crude product was distilled at 60°-65° C./0.03 mbar