Cysteamine → HCID 19361766, compound

Participants

Reaction Conditions

Reaction Steps

1 g of 6-[1,3]dioxolan-2-yl-pyridine-2-carboximidic acid methyl ester (4.80 mmol) and 0.47 g of 2-aminoethanethiol (2.16 mmol) are mixed. The mixture is heated at 130° C. for 1 hour 30 minutes. The reaction mixture is taken up in chloroform, washed with water and then dried over magnesium sulfate. After filtration and evaporation of the solvent, the title product is isolated by chromatography on a silica column (eluent: chloroform/methanol; 98:2). 1.10 g of solid are recovered.

Provenance & Evidence