HCID 178419958, compound → HCID 178519547, compound

HRID 376289Notes

Reaction equation

HRID 376289 reaction equation
[O:1]1CCO[CH:2]1[C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([C:12]2[CH:16]=[CH:15][NH:14][N:13]=2)[N:7]=1>C(Cl)(Cl)Cl.CO>[NH:14]1[CH:15]=[CH:16][C:12]([C:8]2[N:7]=[C:6]([CH:2]=[O:1])[CH:11]=[CH:10][CH:9]=2)=[N:13]1

Participants

3

Reactant 1

HCID 178419958HCID 178419958, compound

Product 1

HCID 178519547HCID 178519547, compound

Reagents, catalysts & solvents 1

HCID 21584188Chloroform methanolSolvent

Procedure

The deprotection of the acetal function of 2-[1,3]dioxolan-2-yl-6-(1H-pyrazol-3-yl)pyridine is carried out on 0.65 g of product (2.99 mmol) according to a protocol similar to that used in stage 5 of Example 7. The title compound is isolated by chromatography on a silica column (eluent: chloroform/methanol; 98:2). 0.31 g of a white foam is obtained.

Sources & evidence

ORD record
ord-6523bea7e44041348a28111cf7835db9
Source dataset
uspto-grants-2000_02
Patent number
US06020345

Reaction notes

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