HCID 19361734, compound → HCID 19361749, compound

Participants

Reaction Steps

A suspension of 0.60 g of 2-[1,3]dioxolan-2-yl-6-isopropenylpyridine (3.15 mmol) and 0.10 g of 10% palladium on carbon, in 7 ml of methanol is stirred vigorously under a low hydrogen pressure for 4 hours at room temperature. The solid is removed by filtration on celite and then the methanol is evaporated off. The title product is isolated by chromatography on a silica column (eluent: chloroform/ethyl acetate; 97:3). 0.40 g of a pale yellow oil is obtained.

Provenance & Evidence