反应详情

To a solution of 3 g of 2'-methylacetophenone in 60 ml of acetic acid was added successively 9.7 ml of 47% hydrobromic acid and 8.6 g of pyridinium hydrobromide perbromide, and the mixture was stirred at room temperature for 1 hour. The reaction mixture was poured into water and extracted with ethyl acetate. The extract was washed with water and a saturated sodium carbonate solution, and dried over anhydrous magnesium sulfate. The drying agent was removed by filtration, and the solvent was removed under reduced pressure to give 5.4 g of the title compound as a colorless oily material.

1. extractionextracted with ethyl acetate
2. washThe extract was washed with water
3. dry with materiala saturated sodium carbonate solution, and dried over anhydrous magnesium sulfate
4. customThe drying agent was removed by filtration
5. customthe solvent was removed under reduced pressure