Sodium Hydroxide → HCID 178514392, compound

Participants

Reaction Steps

0.08 g (0.2 mmol) of the ester from Example 64 were dissolved in 30 ml ethanol followed by addition of 0.4 ml aqueous 2 N sodium hydroxide solution. The mixture was stirred at room temperature for two days, and the mixture was concentrated to dryness under reduced pressure. The residue was dissolved in water, and the solution was neutralized with acetic acid, while the title acid precipitated. It was filtered with suction, washed with water, and dried in vacuo. Yield: 0.045 g (61%) of a beige crystalline solid, m.p. 258-260° C.

Provenance & Evidence