反应详情

A reaction of 115 mmol of 2,5-dibromopyrimidine, 115 mmol of 2-butoxypyrdine-5-boronic acid, 230 mmol of sodium carbonate and 1.2 mmol of tetrakis(triphenylphosphine)palladium(0) in 280 ml of toluene, 140 ml of ethanol and 140 ml of water is carried out analogously to the procedure indicated for precursor 3. Corresponding purification gives 15.9 g (38%) of a colorless solid, m.p. 99-101 ° C.

1. custompurification