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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 376758Generated: October 26, 2026

5-Bromo-2-chloropyrimidine → 2-Chloro-5-(6-hexyloxypyridin-3-yl)pyrimidine

https://huagongshe.com/reaction/376758

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-chloropyrimidineHCID 606665—
Reactant6-Hexyloxypyridine-3-boronic acidHCID 22112571—
Product2-Chloro-5-(6-hexyloxypyridin-3-yl)pyrimidineHCID 19359106—

Reaction Steps

A reaction of 5-bromo-2-chloropyrimidine and 2-hexyloxypyridine-5-boronic acid is carried out analogously to the procedure indicated for precursor 3. Corresponding purification gives a colorless solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06022492
Source datasetuspto-grants-2000_02
ORD IDord-0cc33b8b355b461daae7c2cc00609d0d
Source noteuspto-grants-2000_02