Trifluoroacetic acid → HCID 131721644, compound

HRID 377141Notes

Reaction equation

HRID 377141 reaction equation
C([O:5][C:6](=[O:45])[C@H:7]([CH2:43][SH:44])[NH:8][C:9]([OH:42])([CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41])[C:10]([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])=[O:11])(C)(C)C.FC(F)(F)C(O)=O>>[CH2:12]([C:10](=[O:11])[C:9]([NH:8][C@H:7]([C:6]([OH:45])=[O:5])[CH2:43][SH:44])([OH:42])[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41])[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 131721645HCID 131721645, compound

Product 1

HCID 131721644HCID 131721644, compound

Procedure

N-(α-Tetradecyl-β-hydroxyoctadecanoyl)cysteine tert.-butyl ester (1 g, 1.5 mmol) is treated with anhydrous trifluoroacetic acid for 1/2 h, and the latter is then removed in a rotary evaporator under high vacuum. The residue is dissolved in tert.-butanol and is freeze-dried.

Workup

  1. customthe latter is then removed in a rotary evaporator under high vacuum
  2. dissolutionThe residue is dissolved in tert.-butanol
  3. customis freeze-dried

Sources & evidence

ORD record
ord-f660f3557f794eca9af64ade420c5162
Source dataset
uspto-grants-2000_02
Patent number
US06024964

Reaction notes

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