4-Nitrobenzyl chloride → HCID 19358128, compound

HRID 377165Notes

Reaction equation

HRID 377165 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:14]2[CH:19]([CH2:20][CH3:21])[S:18][C:17](=[O:22])[NH:16][N:15]=2)[CH:6]=[CH:7][C:8]=1[O:9][C:10]([F:13])([F:12])[F:11].[N+:23]([C:26]1[CH:33]=[CH:32][C:29]([CH2:30]Cl)=[CH:28][CH:27]=1)([O-:25])=[O:24]>>[N+:23]([C:26]1[CH:33]=[CH:32][C:29]([CH2:30][N:16]2[N:15]=[C:14]([C:5]3[CH:6]=[CH:7][C:8]([O:9][C:10]([F:12])([F:13])[F:11])=[C:3]([O:2][CH3:1])[CH:4]=3)[CH:19]([CH2:20][CH3:21])[S:18][C:17]2=[O:22])=[CH:28][CH:27]=1)([O-:25])=[O:24]

Participants

3

Reactant 2

HCID 74824-Nitrobenzyl chlorideHCID 9902212HCID 9902212, compound

Product 1

HCID 19358128HCID 19358128, compound

Procedure

In analogy to Example 1, the reaction of 5-(3-methoxy-4-trifluoromethoxyphenyl)-6-ethyl-3,6-dihydro-1, 3,4-thiadiazin-2-one with 4-nitrobenzyl chloride ("C") gives 3-(4-nitrobenzyl)-5-(3-methoxy-4-trifluoromethoxyphenyl)-6-ethyl-3,6-dihydro-1,3,4-thiadiazin-2-one.

Sources & evidence

ORD record
ord-3058b3c4c41b4f428111d5a2091e92d2
Source dataset
uspto-grants-2000_02
Patent number
US06025354

Reaction notes

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