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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 377199Generated: October 30, 2026

HCID 54162563, compound → HCID 19358290, compound

https://huagongshe.com/reaction/377199

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 54162563HCID 54162563—
SolventEthanolHCID 702—
SolventPalladiumHCID 23938—
ProductHCID 19358290HCID 19358290100%

Reaction Steps

The protected amine 2-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]piperidine-1-carboxylic acid benzyl ester (D3, 14 g, 0.037 mol) was dissolved in ethanol (300 ml) and hydrogenated over 10% Pd/C for 18 hours to afford the title compound (9 g, 100%). MH+ 245.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06025367
Source datasetuspto-grants-2000_02
ORD IDord-e06f9d5b5e1d42e88bfac27810c5ca53
Source noteuspto-grants-2000_02