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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 377336Generated: October 30, 2026

HCID 53831028, compound → HCID 53769712, compound

https://huagongshe.com/reaction/377336

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 53831028HCID 53831028—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
SolventTetrahydrofuranHCID 8028—
ProductHCID 53769712HCID 5376971269.7%

Reaction Steps

To a solution of ethyl [3-[2-[(4,5-diphenyloxazol-2-yl)methylene]cyclohexan-1-yl]phenoxy]acetate (300 mg) in a mixture of ethanol (10 ml) and tetrahydrofuran (10 ml) was added 10% palladium on carbon (50 mg). After being stirred for 4 hours under hydrogen atmosphere, the reaction mixture was filtered. The solvent was evaporated in vacuo to give ethyl [3-[2-[(4,5-diphenyloxazol-2-yl)methyl]cyclohexan-1-yl]phenoxy]acetate (210 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06025375
Source datasetuspto-grants-2000_02
ORD IDord-c229a6887ec34237a8bfade9987babf6
Source noteuspto-grants-2000_02