反应详情

Two drops of dimethylformamide and 11.90 g (0.1 mol) of thionyl chloride were added to a solution of 5.00 g (0.02 mol) of methyl 2,4-dichloro-3-hydroxycarbonylbenzoate and 50 ml of dry toluene. The solution was refluxed for 4 hours. After the solvent had been distilled off, 5.35 g of methyl 3-chlorocarbonyl-2,4-dichlorobenzoate were obtained.

1. temperatureThe solution was refluxed for 4 hours
2. distillationAfter the solvent had been distilled off