HRID37759

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11430

Potassium Carbonate

CK2O3

结构：CC(=O)c1ccc(-n2c3ccc(C(C)=O)cc3c3cc(C(=O)c4ccc(F)cc4)ccc32)cc1

HCID66886474

未命名化合物

HCID178418395

未命名化合物

PRODUCTS

生成物

结构：CC(=O)c1ccc(-n2c3ccc(C(C)=O)cc3c3cc(C(=O)c4ccc(Sc5nc6ccccc6s5)cc4)ccc32)cc1

HCID68600484

未命名化合物

PROCEDURE

实验过程

An analogous reaction as described in example 5.a by using 2-mercaptobenzothiazole and 1-{4-[3-acetyl-6-(4-fluoro-benzoyl)-carbazol-9-yl]-phenyl}-ethanone in the presence of potassium carbonate gives the product. The structure is confirmed by the 1H-NMR spectrum (CDCl3). δ [ppm]: 2.74 (s, 3H), 2.75 (s, 3H), 7.35 (t, 1H), 7.47 (t, 2H), 7.52 (d, 1H), 7.72 (d, 2H), 7.77 (d, 1H), 7.86 (d, 2H), 7.92 (d, 2H), 7.96 (d, 1H), 8.03 (d, 1H), 8.15 (d, 1H), 8.28 (d, 2H), 8.71 (s, 1H), 8.81 (s, 1H).

WORKUP

后处理

customAn analogous reaction
customgives the product

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-33cc1cc6355f48cab452c2dd53221d74
来源数据集: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08524425B2
来源说明: uspto-grants-2013_09

反应 SMILES

[SH:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[C:11]([C:14]1[CH:15]=[CH:16][C:17]2[N:18]([C:36]3[CH:41]=[CH:40][C:39]([C:42](=[O:44])[CH3:43])=[CH:38][CH:37]=3)[C:19]3[C:24]([C:25]=2[CH:26]=1)=[CH:23][C:22]([C:27](=[O:35])[C:28]1[CH:33]=[CH:32][C:31](F)=[CH:30][CH:29]=1)=[CH:21][CH:20]=3)(=[O:13])[CH3:12].C(=O)([O-])[O-].[K+].[K+]>>[C:42]([C:39]1[CH:38]=[CH:37][C:36]([N:18]2[C:17]3[CH:16]=[CH:15][C:14]([C:11](=[O:13])[CH3:12])=[CH:26][C:25]=3[C:24]3[C:19]2=[CH:20][CH:21]=[C:22]([C:27](=[O:35])[C:28]2[CH:33]=[CH:32][C:31]([S:1][C:2]4[S:3][C:4]5[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=5[N:6]=4)=[CH:30][CH:29]=2)[CH:23]=3)=[CH:41][CH:40]=1)(=[O:44])[CH3:43]