Potassium Carbonate → HCID 19356156, compound

Participants

Reaction Conditions

Reaction Steps

4.23 g (35 mmol) of 2-fluorobenzonitrile, 6.3 g (35 mmol) of ethyl 3-hydroxyphenylacetate and 4.84 g of potassium carbonate (anhydrous) are dissolved in 40 ml of dimethylformamide and heated with stirring to a temperature of 160° C. Ethyl 3-(2-cyanophenoxy)-phenylacetate is formed takes place [sic]. The mixture is stirred for three hours while maintaining the temperature. The cooled reaction solution is treated with 150 ml of water and extracted with methyl t-butyl ether. The organic phase is separated off, washed with water and NaCl solution and dried. After distilling off the solvent, the product is obtained as an oil.

Provenance & Evidence