反应详情

Hydrazine hydrate (6.5 ml) was added to a solution of 6-chloro-3-methyl-1-(2-methylpropyl)pyrimidine-2,4[1H,3H]-dione (10.0 g) in ethanol (40 ml). The mixture was heated at reflux for 5 hours, cooled to room temperature and then evaporated under reduced pressure. The residue was recrystallised from ethanol to give the subtitle compound (8.8 g).

1. temperatureThe mixture was heated
2. temperatureat reflux for 5 hours
3. customevaporated under reduced pressure
4. customThe residue was recrystallised from ethanol