Tert-Butyl nitrite → HCID 21188131, compound

Participants

Reaction Steps

To a stirred solution of 4-acetyl-5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole (0.4 g) in tetrahydrofuran (2 ml) was added dropwise t-butylnitrite (0.0262 ml). The mixture was heated under reflux for 30 minutes. The reaction mixture was applied to a silica gel (1 g) column and eluted with tetrahydrofuran to provide the title compound as white solid, m.p. 166-168° C.

Provenance & Evidence