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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 377765Generated: October 25, 2026

3,4,5-Trimethoxybenzaldehyde → (Z)-5-fluoro-2-methyl-1-(3,4,5-trimethoxybenzylidene)-3-indenylacetic acid

https://huagongshe.com/reaction/377765

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4,5-TrimethoxybenzaldehydeHCID 6858—
Reactant5-Fluoro-2-methyl-1H-indene-3-acetic acidHCID 3015608—
Product(Z)-5-fluoro-2-methyl-1-(3,4,5-trimethoxybenzylidene)-3-indenylacetic acidHCID 9864863—

Reaction Steps

5-fluoro-2-methylindene-3-acetic acid (see Example 1, Part D) is allowed to react with 3,4,5-trimethoxybenzaldehyde according to the procedure of Example 1, part E to obtain (Z)-5-fluoro-2-methyl-1-(3,4,5-trimethoxybenzylidene)-3-indenylacetic acid. C22H21FO5 : 384.40; m.p. 168° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06028116
Source datasetuspto-grants-2000_02
ORD IDord-c3b98f3c7bc44e99a0796b151b0c93cb
Source noteuspto-grants-2000_02