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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 377903Generated: October 30, 2026

1-(3,5-Difluorophenyl)piperazine → 1-[(2-Methylquinolin-3-yl)aminothiocarbonyl]-4-(3,5-difluorophenyl)piperazine

https://huagongshe.com/reaction/377903

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3,5-Difluorophenyl)piperazineHCID 10987219—
ReactantPhenyl N-(2-methylquinolin-3-yl)thiocarbamateHCID 53717370—
Product1-[(2-Methylquinolin-3-yl)aminothiocarbonyl]-4-(3,5-difluorophenyl)piperazineHCID 8675517074%

Reaction Steps

Phenyl N-(2-methylquinolin-3-yl)thiocarbamate and 1-(3,5-difluorophenyl)piperazine were reacted by the same way with the example 125 to obtain the titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06028195
Source datasetuspto-grants-2000_02
ORD IDord-b169f8dbf78b4c87bded5e0ba1d18f78
Source noteuspto-grants-2000_02