HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Phenyl N-(2-hydroxy-4,5-dimethylphenyl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Phenyl chloroformate | HCID 15891 | — |
| Reactant | 2-Amino-4,5-dimethylphenol | HCID 81099 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Phenyl N-(2-hydroxy-4,5-dimethylphenyl)carbamate | HCID 19356987 | 92% |
Reaction Steps
To 4,5-dimethyl-2-hydroxyaniline(6.80 g, 0.05 mole), methylene chloride(100 ml) was added and then phenyl chloroformate(8.0 g, 0.05 mole) was added slowly. After stirring for 2 hours, addition of water(150 ml), extraction with methylene chloride and column chromatography gave the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06028195 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-38a07a32ca0e4fe0b454bd7ab4861dd0 |
| Source note | uspto-grants-2000_02 |