HCID 19353280, compound → HCID 19353399, compound

HRID 378256Notes

Reaction equation

HRID 378256 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[C:8]3[CH2:9][NH:10][C:11](=[O:23])[C:12]=3[CH:13]=[C:14]3[CH:22]=[CH:21][C:20]4[O:19][CH2:18][O:17][C:16]=4[C:15]=23)=[CH:3][CH:2]=1.C(OCC)(=O)C.[ClH:30]>CO>[ClH:30].[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[C:8]3[CH2:9][NH:10][C:11](=[O:23])[C:12]=3[CH:13]=[C:14]3[CH:22]=[CH:21][C:20]4[O:19][CH2:18][O:17][C:16]=4[C:15]=23)=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 19353280HCID 19353280, compoundHCID 21866389Hydrogen chloride-ethyl acetate

Product 1

HCID 19353399HCID 19353399, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a methanol (20 ml) solution of 8,9-dihydro-10-(4-pyridyl)-7H-1,3-benzodioxolo[4,5-f]isoindol-7-one (120 mg) was added 4N hydrogen chloride-ethyl acetate solution (4 ml) and stirred for 30 minutes. The resultant precipitates were collected by suction and washed with ethyl acetate to give the entitled compound (126 mg).

Workup

  1. customThe resultant precipitates
  2. customwere collected by suction
  3. washwashed with ethyl acetate

Sources & evidence

ORD record
ord-b16246ab7c524a94b702483f4d2672b6
Source dataset
uspto-grants-2000_02
Patent number
US06030967

Reaction notes

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