2-Cyclopentyl-indolizine → 2-Cyclopentyl-5,6,7,8-tetrahydro-indolizine

Participants

Reaction Steps

2-Cyclopentyl-indolizine (0.25 g, 1.35 mmol) was dissolved in methanol (5 mL) and hydrogenated over Raney nickel (50 mg) under balloon pressure at room temperature for 1 h. The reaction mixture was filtered through celite, washing with methanol. Concentration of the filtrate afforded 2-cyclopentyl-5,6,7,8-tetrahydro-indolizine (0.24 g, 94%) as a solid.

Provenance & Evidence