HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Phenylbenzene-1-sulfonyl chloride → N-(4-bromo-3-methyl-5-isoxazolyl)-2-biphenylsulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Phenylbenzene-1-sulfonyl chloride | HCID 2756680 | — |
| Reactant | 4-Bromo-3-methylisoxazol-5-amine | HCID 10487519 | — |
| Product | N-(4-bromo-3-methyl-5-isoxazolyl)-2-biphenylsulfonamide | HCID 15453177 | 71% |
Reaction Steps
N-(4-bromo-3-methyl-5-isoxazolyl)-2-biphenylsulfonamide was prepared in the same manner as described in Example 8b from 5-amino-4-bromo-3-methylisoxazole and 2-biphenylsulfonyl chloride in 71% yield. Purification was achieved by recrystallization from ethyl acetate/hexanes to give a crystalline solid, m.p. 145-147° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06030991 |
| Source dataset | uspto-grants-2000_02 |
| ORD ID | ord-5132a8aa5278454ba9c6fb83b96ede67 |
| Source note | uspto-grants-2000_02 |