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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 378673Generated: October 29, 2026

Carbon Dioxide → 8-(4-Benzyloxy-phenyl)-10-[(2-methoxy-ethyl)-phenyl-carbamoyl]-7-oxo-7H-thieno[2,3-a]quinolizine-2-carboxylic acid

https://huagongshe.com/reaction/378673

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbon DioxideHCID 280—
Reactant8-(4-Benzyloxy-phenyl)-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid (2-methoxy-ethyl)-phenyl-amideHCID 56636258—
Product8-(4-Benzyloxy-phenyl)-10-[(2-methoxy-ethyl)-phenyl-carbamoyl]-7-oxo-7H-thieno[2,3-a]quinolizine-2-carboxylic acidHCID 19353668—

Reaction Steps

By lithiation of 8-(4-benzyloxy-phenyl)-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid (2-methoxy-ethyl)-phenyl-amide and reaction with carbon dioxide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06030984
Source datasetuspto-grants-2000_02
ORD IDord-146f206411834f2080006b52e9180cb1
Source noteuspto-grants-2000_02