Ethanol → HCID 21697690, compound

Participants

Reaction Steps

To the solution of 1,3-dihydro-2,2-dioxo-4-chloro-3-fluoro-7-nitro-2,1-benzisothiazole (100 mg, 0.4 mmol) in ethanol (10 ml), Tin (II) chloride (443 mg, 2.0 mmol) was added. The reaction mixture was stirred at room temperature for about 16 hours. Then all solvent was evaporated. Chromatography of the residue on silica gel (50% Ethyl acetate/Hexane) gave desired product (43 mg, 47%). EI-MS m/z 237.2 (M+).

Provenance & Evidence