Hydrochloric Acid → HCID 178433207, compound

Participants

Reaction Steps

151 mg of butyl {3-[(2-guanidino-4-methyl-thiazole-5-carbonyl)-amino]-propoxy}-acetate are stirred for 5 hrs. in 3 ml of 25% hydrochloric acid. The reaction mixture is evaporated to dryness in a vacuum and the residue is lyophilized from acetic acid. There are obtained 144 mg of [3-[(2-guanidino-4-methyl-thiazole-5-carbonyl)-amino]-propoxy]-acetic acid hydrochloride (1:1), m.p. 48-51° C., MS: 316 (M+H)+.

Provenance & Evidence