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HRID378992

反应详情

EQUATION

反应方程式

HRID 378992 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)COc1cccc(N)c1
HCID10561049

tert-butyl (3-amino-phenoxy)-acetate

C12H17NO3

结构：Cc1nc(NC(=N)N)sc1C(=O)O
HCID178433209

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc(NC(=N)N)sc1C(=O)Nc1cccc(OCC(=O)OC(C)(C)C)c1
HCID178433202

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O.ClCCl
溶剂HCID21226138

未命名化合物

PROCEDURE

实验过程

2-Guanidino-4-methyl-thiazole-5-carboxylic acid is reacted with tert-butyl (3-amino-phenoxy)-acetate in the same manner as in Example 3. Chromatography on silica gel with methylene chloride-ethyl acetate and methylene chloride-alcohol gives 176 mg of tert-butyl {3-[(2-guanidino-4-methyl-thiazole-5-carbonyl)-amino]-phenoxy}-acetate, m.p. 204° C., MS: 406 (M+H)+.