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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 379000생성일: 2026년 10월 25일

Ethyl 4-aminocinnamate → ethyl (E)-3-[4-[[2-(3-benzyl-ureido)-thiazole-4-carbonyl]-amino]-phenyl]-acrylate

https://huagongshe.com/reaction/379000

반응식

참여 물질

역할이름HCID투입량
반응물Ethyl 4-aminocinnamateHCID 736317—
반응물2-(3-Benzyl-ureido)-thiazole-4-carboxylic acidHCID 18322865—
생성물ethyl (E)-3-[4-[[2-(3-benzyl-ureido)-thiazole-4-carbonyl]-amino]-phenyl]-acrylateHCID 86757464—

반응 단계

2-(3-Benzyl-ureido)-thiazole-4-carboxylic acid is coupled with ethyl (E)-3-(4-amino-phenyl)-acrylate in analogy to Example 11 After chromatography on silica gel with methylene chloride-ethanol 98:2 and crystallization from ether there is obtained ethyl (E)-3-[4-[[2-(3-benzyl-ureido)-thiazole-4-carbonyl]-amino]-phenyl]-acrylate, m.p. 207° C., MS: 451 (M+H)+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06297266B1
출처 데이터셋uspto-grants-2001_10
ORD IDord-955604ee1fb3422da5faf1ba4ed2db20
출처 메모uspto-grants-2001_10