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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 379026Generated: October 31, 2026

2-Hydroxy-4-imidazol-1-ylmethyl-benzonitrile → 2-(Biphenyl-4-ylmethoxy)-4-imidazol-1-ylmethyl-benzonitrile

https://huagongshe.com/reaction/379026

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Hydroxy-4-imidazol-1-ylmethyl-benzonitrileHCID 21697028—
Reactant4-(Iodomethyl)biphenylHCID 21909974—
Product2-(Biphenyl-4-ylmethoxy)-4-imidazol-1-ylmethyl-benzonitrileHCID 9951007—

Reaction Steps

Following the procedure described in Example 2, Step E but using 2-hydroxy-4-imidazol-1-ylmethyl-benzonitrile (as described in Step F) and biphenyl-4-ylmethyl iodide as starting materials, the title compound was obtained as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06297239B1
Source datasetuspto-grants-2001_10
ORD IDord-a8bc31dadcec409bb8d84f586d633be9
Source noteuspto-grants-2001_10