反应详情

Cool the 1-(t-butoxycarbonyl)-4-(1-(4-fluoro-benzyl)-1H-benzoimidazole-2-carbonyl)-piperidine in an ice bath. Add trifluoroacetic acid and mix. After 15 minutes, add diethyl ether to give a residue. Collect the residue by filtration and dry under vacuum. Recrystallize from ethanol/ether and dry resulting solid under vacuum to give the title compound.

1. customto give a residue
2. customCollect the residue
3. filtrationby filtration
4. customdry under vacuum
5. customRecrystallize from ethanol/ether
6. customdry
7. customresulting solid under vacuum