HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(1-(4-fluorobenzyl)-1H-benzoimidazol-2-yl)-4-hydroxypiperidine → N-Methyl-N-(4-(4-(1-(4-fluorobenzyl)-1H-benzoimidazol-2-yl)-4-hydroxypiperidin-1-yl)-2-(4-methoxyphenyl)butyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(1-(4-fluorobenzyl)-1H-benzoimidazol-2-yl)-4-hydroxypiperidine | HCID 15542885 | — |
| Reactant | N-methyl-N-(2-(4-methoxyphenyl)-4-methanesulfonylbutyl)benzamide | HCID 18354479 | — |
| Product | N-Methyl-N-(4-(4-(1-(4-fluorobenzyl)-1H-benzoimidazol-2-yl)-4-hydroxypiperidin-1-yl)-2-(4-methoxyphenyl)butyl)benzamide | HCID 15870531 | — |
Reaction Steps
Prepare by the method of Example 1.7 using N-methyl-N-(2-(4-methoxyphenyl)-4-methanesulfonylbutyl)benzamide and 4-(1-(4-fluorobenzyl)-1H-benzoimidazol-2-yl)-4-hydroxypiperidine to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06297259B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-aa7b9d92a1b54dd094672cedca202f92 |
| Source note | uspto-grants-2001_10 |