HRID37945

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2724519

3,4-Difluorobenzoyl chloride

C7H3ClF2O

结构：CCOC(=O)C1=CNCC(C)(C)c2c1[nH]c1cc(N(C)Cc3ccccc3)ccc21

HCID11246670

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)C1=CN(C(=O)c2ccc(F)cc2)CC(C)(C)c2c1[nH]c1cc(N(Cc3ccccc3)Cc3ccccc3)ccc21

HCID10393823

未命名化合物

PROCEDURE

实验过程

In a manner similar to Example 2A, but using ethyl 8-(benzyl(methyl)amino)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate and 3,4-difluorobenzoyl chloride, the following compound was prepared:

WORKUP

后处理

customthe following compound was prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a23187c2687440c6bd0b1540d35269aa
来源数据集: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08524704B2
来源说明: uspto-grants-2013_09

反应 SMILES

[CH2:1]([N:8]([CH3:30])[C:9]1[CH:10]=[CH:11][C:12]2[C:13]3[C:22]([CH3:24])([CH3:23])[CH2:21][NH:20][CH:19]=[C:18]([C:25]([O:27][CH2:28][CH3:29])=[O:26])[C:14]=3[NH:15][C:16]=2[CH:17]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.F[C:32]1[CH:33]=[C:34]([CH:38]=[CH:39][C:40]=1[F:41])[C:35](Cl)=[O:36]>>[CH2:28]([O:27][C:25]([C:18]1[C:14]2[NH:15][C:16]3[CH:17]=[C:9]([N:8]([CH2:30][C:2]4[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=4)[CH2:1][C:2]4[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=4)[CH:10]=[CH:11][C:12]=3[C:13]=2[C:22]([CH3:24])([CH3:23])[CH2:21][N:20]([C:35](=[O:36])[C:34]2[CH:38]=[CH:39][C:40]([F:41])=[CH:32][CH:33]=2)[CH:19]=1)=[O:26])[CH3:29]