化工社化工社 化学情報印刷レポート · 研究参考用
3,4-Difluorobenzoyl chloride → 8-Dibenzylamino-3-(4-fluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-B]indole-5-carboxylic acid ethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3,4-Difluorobenzoyl chloride | HCID 2724519 | — |
| 反応物 | Azepino[4,5-b]indole-5-carboxylic acid, 1,2,3,6-tetrahydro-1,1-dimethyl-8-[methyl(phenylmethyl)amino]-, ethyl ester | HCID 11246670 | — |
| 生成物 | 8-Dibenzylamino-3-(4-fluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-B]indole-5-carboxylic acid ethyl ester | HCID 10393823 | — |
反応手順
In a manner similar to Example 2A, but using ethyl 8-(benzyl(methyl)amino)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate and 3,4-difluorobenzoyl chloride, the following compound was prepared:
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08524704B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-a23187c2687440c6bd0b1540d35269aa |
| 出典メモ | uspto-grants-2013_09 |