HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Trifluoroacetylamino-quinoline → N-(1,2,3,4-tetrahydro-6-quinolyl)trifluoroacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Trifluoroacetylamino-quinoline | HCID 10399371 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | N-(1,2,3,4-tetrahydro-6-quinolyl)trifluoroacetamide | HCID 10421907 | — |
Reaction Steps
2,4 g (0.01 mol) of 6-trifluoroacetylamino-quinoline are dissolved in 20 ml glacial acetic acid and hydrogenated for I hour with 0.6 g platinum oxide at 3 bar. Then the catalyst is suction filtered and the solution is concentrated by evaporation. The residue is washed with a little sodium hydrogen carbonate solution and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06300342B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-6bb49db1d3da4364b87f89882f92cf6a |
| Source note | uspto-grants-2001_10 |