HCID 9823694, compound → HCID 9823693, compound

HRID 379711Notes

Reaction equation

HRID 379711 reaction equation
[CH:1]([NH:4][CH2:5][CH2:6][O:7][C:8]1[CH:26]=[CH:25][C:11]([NH:12][C:13](=[O:24])[C:14]2[C:19]([O:20][CH3:21])=[CH:18][CH:17]=[CH:16][C:15]=2[O:22][CH3:23])=[CH:10][C:9]=1[O:27][CH3:28])([CH3:3])[CH3:2].[ClH:29].C(O)C>C(O)(C)C>[ClH:29].[CH:1]([NH:4][CH2:5][CH2:6][O:7][C:8]1[CH:26]=[CH:25][C:11]([NH:12][C:13](=[O:24])[C:14]2[C:19]([O:20][CH3:21])=[CH:18][CH:17]=[CH:16][C:15]=2[O:22][CH3:23])=[CH:10][C:9]=1[O:27][CH3:28])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 9823694HCID 9823694, compoundHCID 21887872Ethanol hydrochloride

Product 1

HCID 9823693HCID 9823693, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

4′-[2-(Isopropylamino)ethoxy]-2,6-dimethoxy-3′-methoxybenzanilide (1.0 g) solution in isopropylalcohol (5 ml) was added with 1N HCl/ethanol (3.9 ml) and the mixture was stirred. Crystals separated were collected by filtration, washed with isopropylalcohol (5 ml) and dried under vacuum to obtain 4′-[2-(isopropylamino)ethoxy]-2,6-dimethoxy-3′-methoxybenzanilide hydrochloride (1.04 g) as white crystal.

Workup

  1. customCrystals separated
  2. filtrationwere collected by filtration
  3. washwashed with isopropylalcohol (5 ml)
  4. customdried under vacuum

Sources & evidence

ORD record
ord-ec527e27bdd74f9a9e0f32eb37486303
Source dataset
uspto-grants-2001_10
Patent number
US06300368B1

Reaction notes

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