Potassium Bromide → HCID 18368077, compound

HRID 379736Notes

Reaction equation

[C:1]([NH:4][C:5]1[C:13]2[C:8](=[CH:9][C:10]([Cl:14])=[CH:11][CH:12]=2)[N:7](C(OCC)=O)[C:6]=1[C:20](=[O:28])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[Cl:27])(=[O:3])[CH3:2].[K+].[Br-]>>[C:1]([NH:4][C:5]1[C:13]2[C:8](=[CH:9][C:10]([Cl:14])=[CH:11][CH:12]=2)[NH:7][C:6]=1[C:20](=[O:28])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[Cl:27])(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 18367930HCID 18367930, compound

Product 1

HCID 18368077HCID 18368077, compound

Procedure

The title compound was prepared according to the procedure described in step 2 of Example 2 (Method A) from 3-acetylamino-6-chloro-2-(2-chlorobenzoyl)-1-(ethoxycarbonyl)indole (step 1). 1H-NMR (CDCl3) δ: 9.58 (1H, br s), 8.51 (1H, br s), 8.19 (1H, d, J=8.8 Hz), 7.52-7.03 (6H, m), 2.18 (3H, s) IR (KBr) ν: 3300, 1680, 1620, 1580, 1540, 1340, 1320, 1240, 1060, 1020, 920, 760, 740 cm−1

Sources & evidence

ORD record: ord-3792d017760e42cfa714aa1767de346b
Source dataset: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06300363B1

Reaction notes

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