HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Acetoxyisobutyroyl chloride → 3-(2-Acetoxyisobutyrylamino)-2-benzoyl-6-chloroindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Acetoxyisobutyroyl chloride | HCID 123496 | — |
| Reactant | 3-Amino-2-benzoyl-6-chloroindole | HCID 18367972 | — |
| Product | 3-(2-Acetoxyisobutyrylamino)-2-benzoyl-6-chloroindole | HCID 18367845 | — |
Reaction Steps
The title compound was prepared according to the procedure described in Example 19 employing 3-amino-2-benzoyl-6-chloroindole (Example 1) and 2-acetoxyisobutyryl chloride. m.p.: 162-165° C. 1H-NMR (CDCl3) δ: 10.78 (1H, br s), 8.36 (1H, d, J=9.2 Hz), 8.28 (1H, br s), 7.85-7.76 (2H, m), 7.68-7.53 (3H, m), 7.26 (1H, d, J=1.8 Hz), 7.08 (1H, dd, J=1.8, 9.2 Hz), 2.21 (3H, s), 1.75 (6H, s)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06300363B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-2ad7a8dbb92d4810b80ddb4d46e14baa |
| Source note | uspto-grants-2001_10 |